Functional compartmentalization of Rad9 and Hus1 reveals diverse assembly of the 9‐1‐1 complex components during the DNA damage response in Leishmania

The Rad9‐Rad1‐Hus1 (9‐1‐1) complex is a key component in the coordination of DNA damage sensing, cell cycle progression and DNA repair pathways in eukaryotic cells. This PCNA‐related trimer is loaded onto RPA‐coated single stranded DNA and interacts with ATR kinase to mediate effective checkpoint si...

Descripción completa

Detalles Bibliográficos
Autores principales: Damasceno, Jeziel D., Obonaga, Ricardo, Santos, Elaine V., Scott, Alan, McCulloch, Richard, Tosi, Luiz R. O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453112/
https://www.ncbi.nlm.nih.gov/pubmed/27301589
http://dx.doi.org/10.1111/mmi.13441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453112/
https://www.ncbi.nlm.nih.gov/pubmed/27301589
http://dx.doi.org/10.1111/mmi.13441

Ejemplares similares