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Chemical probes targeting epigenetic proteins: Applications beyond oncology

Epigenetic chemical probes are potent, cell-active, small molecule inhibitors or antagonists of specific domains in a protein; they have been indispensable for studying bromodomains and protein methyltransferases. The Structural Genomics Consortium (SGC), comprising scientists from academic and phar...

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Detalles Bibliográficos
Autores principales: Ackloo, Suzanne, Brown, Peter J., Müller, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453191/
https://www.ncbi.nlm.nih.gov/pubmed/28080202
http://dx.doi.org/10.1080/15592294.2017.1279371