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Chemical probes targeting epigenetic proteins: Applications beyond oncology
Epigenetic chemical probes are potent, cell-active, small molecule inhibitors or antagonists of specific domains in a protein; they have been indispensable for studying bromodomains and protein methyltransferases. The Structural Genomics Consortium (SGC), comprising scientists from academic and phar...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453191/ https://www.ncbi.nlm.nih.gov/pubmed/28080202 http://dx.doi.org/10.1080/15592294.2017.1279371 |