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RNA-DNA hybrid (R-loop) immunoprecipitation mapping: an analytical workflow to evaluate inherent biases

The impact of R-loops on the physiology and pathology of chromosomes has been demonstrated extensively by chromatin biology research. The progress in this field has been driven by technological advancement of R-loop mapping methods that largely relied on a single approach, DNA-RNA immunoprecipitatio...

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Detalles Bibliográficos
Autores principales: Halász, László, Karányi, Zsolt, Boros-Oláh, Beáta, Kuik-Rózsa, Tímea, Sipos, Éva, Nagy, Éva, Mosolygó-L, Ágnes, Mázló, Anett, Rajnavölgyi, Éva, Halmos, Gábor, Székvölgyi, Lóránt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453320/
https://www.ncbi.nlm.nih.gov/pubmed/28341774
http://dx.doi.org/10.1101/gr.219394.116