Microfluidic Mobility Shift Assay for Real-Time Analysis of Peptide N-Palmitoylation

The Hedgehog pathway is a key developmental signaling pathway but is also implicated in many types of cancer. The extracellular signaling protein Sonic hedgehog (Shh) requires dual lipidation for functional signaling, whereby N-terminal palmitoylation is performed by the enzyme Hedgehog acyltransfer...

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Detalles Bibliográficos
Autores principales: Lanyon-Hogg, Thomas, Patel, Neki V., Ritzefeld, Markus, Boxall, Katherine J., Burke, Rosemary, Blagg, Julian, Magee, Anthony I., Tate, Edward W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453399/
https://www.ncbi.nlm.nih.gov/pubmed/28296537
http://dx.doi.org/10.1177/2472555216689529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453399/
https://www.ncbi.nlm.nih.gov/pubmed/28296537
http://dx.doi.org/10.1177/2472555216689529

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