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Microfluidic Mobility Shift Assay for Real-Time Analysis of Peptide N-Palmitoylation
The Hedgehog pathway is a key developmental signaling pathway but is also implicated in many types of cancer. The extracellular signaling protein Sonic hedgehog (Shh) requires dual lipidation for functional signaling, whereby N-terminal palmitoylation is performed by the enzyme Hedgehog acyltransfer...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
SAGE Publications
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453399/ https://www.ncbi.nlm.nih.gov/pubmed/28296537 http://dx.doi.org/10.1177/2472555216689529 |