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An androgen response element driven reporter assay for the detection of androgen receptor activity in prostate cells

The androgen receptor (AR) transcription factor plays a key role in the development and progression of prostate cancer, as is evident from the efficacy of androgen-deprivation therapy, AR is also the most frequently mutated gene, in castration resistant prostate cancer (CRPC). AR has therefore becom...

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Detalles Bibliográficos
Autores principales: Azeem, Waqas, Hellem, Margrete Reime, Olsen, Jan Roger, Hua, Yaping, Marvyin, Kristo, Qu, Yi, Lin, Biaoyang, Ke, Xisong, Øyan, Anne Margrete, Kalland, Karl-Henning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453475/
https://www.ncbi.nlm.nih.gov/pubmed/28570625
http://dx.doi.org/10.1371/journal.pone.0177861