Circulating FGF19 closely correlates with bile acid synthesis and cholestasis in patients with primary biliary cirrhosis

BACKGROUND AND AIM: Bile acid (BA) synthesis in the liver is regulated by Fibroblast Growth Factor 19 (FGF19) secreted from the ileum as an enterohepatic feedback mechanism. Although FGF19 mRNA is absent in normal liver, FGF19 gene expression was reported to increase in response to both extrahepatic...

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Detalles Bibliográficos
Autores principales: Li, Zhanyi, Lin, Bingliang, Lin, Guoli, Wu, Yuankai, Jie, Yusheng, Li, Xiangyong, Ko, Brian, Chong, Yutian, Luo, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453554/
https://www.ncbi.nlm.nih.gov/pubmed/28570655
http://dx.doi.org/10.1371/journal.pone.0178580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453554/
https://www.ncbi.nlm.nih.gov/pubmed/28570655
http://dx.doi.org/10.1371/journal.pone.0178580

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