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Evolution of Salmonella Typhi outer membrane protein-specific T and B cell responses in humans following oral Ty21a vaccination: A randomized clinical trial

Vaccination against complex pathogens such as typhoidal and non-typhoidal Salmonella requires the concerted action of different immune effector mechanisms. Outer membrane proteins (Omps) of Salmonella Typhi are potent immunogens, which elicit long-lasting and protective immunity. Here, we followed t...

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Detalles Bibliográficos
Autores principales: Carreño, Juan Manuel, Perez-Shibayama, Christian, Gil-Cruz, Cristina, Lopez-Macias, Constantino, Vernazza, Pietro, Ludewig, Burkhard, Albrich, Werner C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453566/
https://www.ncbi.nlm.nih.gov/pubmed/28570603
http://dx.doi.org/10.1371/journal.pone.0178669