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Depletion of ATP and glucose in advanced human atherosclerotic plaques

OBJECTIVE: Severe hypoxia develops close to the necrotic core of advanced human atherosclerotic plaques, but the energy metabolic consequences of this hypoxia are not known. In animal models, plaque hypoxia is also associated with depletion of glucose and ATP. ATP depletion may impair healing of pla...

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Detalles Bibliográficos
Autores principales: Ekstrand, Matias, Widell, Emma, Hammar, Anna, Akyürek, Levent M., Johansson, Martin, Fagerberg, Björn, Bergström, Göran, Levin, Malin C., Fogelstrand, Per, Borén, Jan, Levin, Max
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453577/
https://www.ncbi.nlm.nih.gov/pubmed/28570702
http://dx.doi.org/10.1371/journal.pone.0178877