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Combining inferred regulatory and reconstructed metabolic networks enhances phenotype prediction in yeast

Gene regulatory and metabolic network models have been used successfully in many organisms, but inherent differences between them make networks difficult to integrate. Probabilistic Regulation Of Metabolism (PROM) provides a partial solution, but it does not incorporate network inference and underpe...

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Detalles Bibliográficos
Autores principales: Wang, Zhuo, Danziger, Samuel A., Heavner, Benjamin D., Ma, Shuyi, Smith, Jennifer J., Li, Song, Herricks, Thurston, Simeonidis, Evangelos, Baliga, Nitin S., Aitchison, John D., Price, Nathan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453602/
https://www.ncbi.nlm.nih.gov/pubmed/28520713
http://dx.doi.org/10.1371/journal.pcbi.1005489