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Suppression of asparaginyl endopeptidase attenuates breast cancer-induced bone pain through inhibition of neurotrophin receptors

OBJECTIVE: Cancer-induced bone pain is a common clinical problem in breast cancer patients with bone metastasis. However, the mechanisms driving cancer-induced bone pain are poorly known. Recent studies show that a novel protease, asparaginyl endopeptidase (AEP) plays crucial roles in breast cancer...

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Detalles Bibliográficos
Autores principales: Yao, Peng, Ding, Yuanyuan, Han, Zhenkai, Mu, Ying, Hong, Tao, Zhu, Yongqiang, Li, Hongxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453632/
https://www.ncbi.nlm.nih.gov/pubmed/28554249
http://dx.doi.org/10.1177/1744806917708127