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Cathelicidin-trypsin inhibitor loop conjugate represents a promising antibiotic candidate with protease stability

Cathelicidins are regarded as promising antibiotics due to their capability against antibiotic-resistant bacteria without cytotoxicity. However, some concerns about the balance of cytotoxicity and antimicrobial activity, weak stability and enzymatic susceptibility sually restrict their therapeutic u...

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Detalles Bibliográficos
Autores principales: Yu, Haining, Wang, Chen, Feng, Lan, Cai, Shasha, Liu, Xuelian, Qiao, Xue, Shi, Nannan, Wang, Hui, Wang, Yipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453931/
https://www.ncbi.nlm.nih.gov/pubmed/28572668
http://dx.doi.org/10.1038/s41598-017-02050-2