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Cathelicidin-trypsin inhibitor loop conjugate represents a promising antibiotic candidate with protease stability
Cathelicidins are regarded as promising antibiotics due to their capability against antibiotic-resistant bacteria without cytotoxicity. However, some concerns about the balance of cytotoxicity and antimicrobial activity, weak stability and enzymatic susceptibility sually restrict their therapeutic u...
Autores principales: | Yu, Haining, Wang, Chen, Feng, Lan, Cai, Shasha, Liu, Xuelian, Qiao, Xue, Shi, Nannan, Wang, Hui, Wang, Yipeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453931/ https://www.ncbi.nlm.nih.gov/pubmed/28572668 http://dx.doi.org/10.1038/s41598-017-02050-2 |
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