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Release of Cytochrome C from Bax Pores at the Mitochondrial Membrane

How cytochrome C is released from the mitochondria to the cytosol via Bax oligomeric pores, a process which is required for apoptosis, is still a mystery. Based on experimentally measured residue-residue distances, we recently solved the first atomic model for Bax oligomeric pores at the membranes u...

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Detalles Bibliográficos
Autores principales: Zhang, Mingzhen, Zheng, Jie, Nussinov, Ruth, Ma, Buyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453941/
https://www.ncbi.nlm.nih.gov/pubmed/28572603
http://dx.doi.org/10.1038/s41598-017-02825-7