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Probing the action of a novel anti-leukaemic drug therapy at the single cell level using modern vibrational spectroscopy techniques

Acute myeloid leukaemia (AML) is a life threatening cancer for which there is an urgent clinical need for novel therapeutic approaches. A redeployed drug combination of bezafibrate and medroxyprogesterone acetate (BaP) has shown anti-leukaemic activity in vitro and in vivo. Elucidation of the BaP me...

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Detalles Bibliográficos
Autores principales: Denbigh, Joanna L., Perez-Guaita, David, Vernooij, Robbin R., Tobin, Mark J., Bambery, Keith R., Xu, Yun, Southam, Andrew D., Khanim, Farhat L., Drayson, Mark T., Lockyer, Nicholas P., Goodacre, Royston, Wood, Bayden R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453947/
https://www.ncbi.nlm.nih.gov/pubmed/28572622
http://dx.doi.org/10.1038/s41598-017-02069-5