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Probing the action of a novel anti-leukaemic drug therapy at the single cell level using modern vibrational spectroscopy techniques
Acute myeloid leukaemia (AML) is a life threatening cancer for which there is an urgent clinical need for novel therapeutic approaches. A redeployed drug combination of bezafibrate and medroxyprogesterone acetate (BaP) has shown anti-leukaemic activity in vitro and in vivo. Elucidation of the BaP me...
Autores principales: | Denbigh, Joanna L., Perez-Guaita, David, Vernooij, Robbin R., Tobin, Mark J., Bambery, Keith R., Xu, Yun, Southam, Andrew D., Khanim, Farhat L., Drayson, Mark T., Lockyer, Nicholas P., Goodacre, Royston, Wood, Bayden R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453947/ https://www.ncbi.nlm.nih.gov/pubmed/28572622 http://dx.doi.org/10.1038/s41598-017-02069-5 |
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