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Cell-free DNA from human plasma and serum differs in content of telomeric sequences and its ability to promote immune response

Circulating cell-free DNA (cfDNA) may be involved in immune response regulation. We studied the variations in abundance of telomeric sequences in plasma and serum in young healthy volunteers and the ability of cfDNA contained in these samples to co-activate the TNF-α m RNA expression in monocytes. W...

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Detalles Bibliográficos
Autores principales: Zinkova, Alzbeta, Brynychova, Iva, Svacina, Alexander, Jirkovska, Marie, Korabecna, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453964/
https://www.ncbi.nlm.nih.gov/pubmed/28572683
http://dx.doi.org/10.1038/s41598-017-02905-8