Human papilloma virus E7 oncoprotein abrogates the p53-p21-DREAM pathway

High risk human papilloma viruses cause several types of cancer. The HPV oncoproteins E6 and E7 are essential for oncogenic cell transformation. E6 mediates the degradation of the tumor suppressor p53, and E7 can form complexes with the retinoblastoma pRB tumor suppressor. Recently, it has been show...

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Detalles Bibliográficos
Autores principales: Fischer, Martin, Uxa, Sigrid, Stanko, Clara, Magin, Thomas M., Engeland, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453983/
https://www.ncbi.nlm.nih.gov/pubmed/28572607
http://dx.doi.org/10.1038/s41598-017-02831-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453983/
https://www.ncbi.nlm.nih.gov/pubmed/28572607
http://dx.doi.org/10.1038/s41598-017-02831-9

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