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Use of Patterned Collagen Coated Slides to Study Normal and Scleroderma Lung Fibroblast Migration

Systemic sclerosis (SSc) is a spreading fibrotic disease affecting the skin and internal organs. We aimed to model pathogenic fibroblast migration in SSc in order to identify enhancing factors, measure the effect of migrating cells on underlying extracellular matrix (ECM) and test possible therapeut...

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Detalles Bibliográficos
Autores principales: Ahmed Abdi, Bahja, Lopez, Henry, Karrar, Sarah, Renzoni, Elisabetta, Wells, Athol, Tam, Angela, Etomi, Oseme, Hsuan, J. Justin, Martin, George R., Shiwen, Xu, Denton, Christopher P., Abraham, David, Stratton, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453993/
https://www.ncbi.nlm.nih.gov/pubmed/28572686
http://dx.doi.org/10.1038/s41598-017-02621-3