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Novel approach for accurate tissue-based protein colocalization and proximity microscopy

Fluorescence colocalization microscopy is frequently used to assess potential links between distinct molecules; however, this method can lead to striking false-positive results and erroneous conclusions. Here we developed a novel approach with more sophisticated mathematical colocalization analyses...

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Detalles Bibliográficos
Autores principales: Lutz, Mirjam I., Schwaiger, Carmen, Hochreiter, Bernhard, Kovacs, Gabor G., Schmid, Johannes A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454019/
https://www.ncbi.nlm.nih.gov/pubmed/28572629
http://dx.doi.org/10.1038/s41598-017-02735-8