Bi-specific molecule against EGFR and death receptors simultaneously targets proliferation and death pathways in tumors

Developing therapeutics that target multiple receptor signaling pathways in tumors is critical as therapies targeting single specific biomarker/pathway have shown limited efficacy in patients with cancer. In this study, we extensively characterized a bi-functional molecule comprising of epidermal gr...

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Detalles Bibliográficos
Autores principales: Zhu, Yanni, Bassoff, Nicole, Reinshagen, Clemens, Bhere, Deepak, Nowicki, Michal O., Lawler, Sean E., Roux, Jérémie, Shah, Khalid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454031/
https://www.ncbi.nlm.nih.gov/pubmed/28572590
http://dx.doi.org/10.1038/s41598-017-02483-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454031/
https://www.ncbi.nlm.nih.gov/pubmed/28572590
http://dx.doi.org/10.1038/s41598-017-02483-9

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