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Bi-specific molecule against EGFR and death receptors simultaneously targets proliferation and death pathways in tumors
Developing therapeutics that target multiple receptor signaling pathways in tumors is critical as therapies targeting single specific biomarker/pathway have shown limited efficacy in patients with cancer. In this study, we extensively characterized a bi-functional molecule comprising of epidermal gr...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454031/ https://www.ncbi.nlm.nih.gov/pubmed/28572590 http://dx.doi.org/10.1038/s41598-017-02483-9 |