Evidence for shear-mediated Ca(2+) entry through mechanosensitive cation channels in human platelets and a megakaryocytic cell line

The role of mechanosensitive (MS) Ca(2+)-permeable ion channels in platelets is unclear, despite the importance of shear stress in platelet function and life-threatening thrombus formation. We therefore sought to investigate the expression and functional relevance of MS channels in human platelets....

Descripción completa

Detalles Bibliográficos
Autores principales: Ilkan, Zeki, Wright, Joy R., Goodall, Alison H., Gibbins, Jonathan M., Jones, Chris I., Mahaut-Smith, Martyn P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454102/
https://www.ncbi.nlm.nih.gov/pubmed/28416610
http://dx.doi.org/10.1074/jbc.M116.766196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454102/
https://www.ncbi.nlm.nih.gov/pubmed/28416610
http://dx.doi.org/10.1074/jbc.M116.766196

Ejemplares similares