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Structure of the WipA protein reveals a novel tyrosine protein phosphatase effector from Legionella pneumophila

Legionnaires' disease is a severe form of pneumonia caused by the bacterium Legionella pneumophila. L. pneumophila pathogenicity relies on secretion of more than 300 effector proteins by a type IVb secretion system. Among these Legionella effectors, WipA has been primarily studied because of it...

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Detalles Bibliográficos
Autores principales: Pinotsis, Nikos, Waksman, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454105/
https://www.ncbi.nlm.nih.gov/pubmed/28389563
http://dx.doi.org/10.1074/jbc.M117.781948