EGF-mediated inhibition of ubiquitin-specific peptidase 24 expression has a crucial role in tumorigenesis

In this study, several cancer-related proteins (Bax, p300, E2F4 and securin) have been proven to be substrates of ubiquitin-specific peptidase 24 (USP24), and relevance has been shown between USP24 and its substrates in samples from clinical lung cancer patients. Silencing USP24 increases the cancer...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, S-A, Wang, Y-C, Chuang, Y-P, Huang, Y-H, Su, W-C, Chang, W-C, Hung, J-J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454318/
https://www.ncbi.nlm.nih.gov/pubmed/27991932
http://dx.doi.org/10.1038/onc.2016.445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454318/
https://www.ncbi.nlm.nih.gov/pubmed/27991932
http://dx.doi.org/10.1038/onc.2016.445

Ejemplares similares