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Cancer-FOXP3 directly activated CCL5 to recruit FOXP3(+)Treg cells in pancreatic ductal adenocarcinoma

Forkheadbox protein 3 (FOXP3), initially identified as a key transcription factor for regulatory T cells (Treg cells), was also expressed in many tumors including pancreatic ductal adenocarcinoma (PDAC). However, its role in PDAC progression remains elusive. In this study, we utilized 120 PDAC tissu...

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Detalles Bibliográficos
Autores principales: Wang, X, Lang, M, Zhao, T, Feng, X, Zheng, C, Huang, C, Hao, J, Dong, J, Luo, L, Li, X, Lan, C, Yu, W, Yu, M, Yang, S, Ren, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454319/
https://www.ncbi.nlm.nih.gov/pubmed/27991933
http://dx.doi.org/10.1038/onc.2016.458