An optimized strategy to measure protein stability highlights differences between cold and hot unfolded states

Macromolecular crowding ought to stabilize folded forms of proteins, through an excluded volume effect. This explanation has been questioned and observed effects attributed to weak interactions with other cell components. Here we show conclusively that protein stability is affected by volume exclusi...

Descripción completa

Detalles Bibliográficos
Autores principales: Alfano, Caterina, Sanfelice, Domenico, Martin, Stephen R., Pastore, Annalisa, Temussi, Piero Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454340/
https://www.ncbi.nlm.nih.gov/pubmed/28516908
http://dx.doi.org/10.1038/ncomms15428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454340/
https://www.ncbi.nlm.nih.gov/pubmed/28516908
http://dx.doi.org/10.1038/ncomms15428

Ejemplares similares