Genetic architecture of epigenetic and neuronal ageing rates in human brain regions

Identifying genes regulating the pace of epigenetic ageing represents a new frontier in genome-wide association studies (GWASs). Here using 1,796 brain samples from 1,163 individuals, we carry out a GWAS of two DNA methylation-based biomarkers of brain age: the epigenetic ageing rate and estimated p...

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Detalles Bibliográficos
Autores principales: Lu, Ake T., Hannon, Eilis, Levine, Morgan E., Crimmins, Eileen M., Lunnon, Katie, Mill, Jonathan, Geschwind, Daniel H., Horvath, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454371/
https://www.ncbi.nlm.nih.gov/pubmed/28516910
http://dx.doi.org/10.1038/ncomms15353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454371/
https://www.ncbi.nlm.nih.gov/pubmed/28516910
http://dx.doi.org/10.1038/ncomms15353

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