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Lhx1/5 control dendritogenesis and spine morphogenesis of Purkinje cells via regulation of Espin
In the cerebellar cortex, Purkinje cells (PCs) receive signals from different inputs through their extensively branched dendrites and serve as an integration centre. Defects in the dendritic development of PCs thus disrupt cerebellar circuitry and cause ataxia. Here we report that specific inactivat...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454373/ https://www.ncbi.nlm.nih.gov/pubmed/28516904 http://dx.doi.org/10.1038/ncomms15079 |