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Lhx1/5 control dendritogenesis and spine morphogenesis of Purkinje cells via regulation of Espin

In the cerebellar cortex, Purkinje cells (PCs) receive signals from different inputs through their extensively branched dendrites and serve as an integration centre. Defects in the dendritic development of PCs thus disrupt cerebellar circuitry and cause ataxia. Here we report that specific inactivat...

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Detalles Bibliográficos
Autores principales: Lui, Nga Chu, Tam, Wing Yip, Gao, Caiji, Huang, Jian-Dong, Wang, Chi Chiu, Jiang, Liwen, Yung, Wing Ho, Kwan, Kin Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454373/
https://www.ncbi.nlm.nih.gov/pubmed/28516904
http://dx.doi.org/10.1038/ncomms15079