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Histone deacetylase 10 structure and molecular function as a polyamine deacetylase

Cationic polyamines such as spermidine and spermine are critical in all forms of life, as they regulate the function of biological macromolecules. Intracellular polyamine metabolism is regulated by reversible acetylation and dysregulated polyamine metabolism is associated with neoplastic diseases su...

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Detalles Bibliográficos
Autores principales: Hai, Yang, Shinsky, Stephen A., Porter, Nicholas J., Christianson, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454378/
https://www.ncbi.nlm.nih.gov/pubmed/28516954
http://dx.doi.org/10.1038/ncomms15368