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Histone deacetylase 10 structure and molecular function as a polyamine deacetylase
Cationic polyamines such as spermidine and spermine are critical in all forms of life, as they regulate the function of biological macromolecules. Intracellular polyamine metabolism is regulated by reversible acetylation and dysregulated polyamine metabolism is associated with neoplastic diseases su...
Autores principales: | Hai, Yang, Shinsky, Stephen A., Porter, Nicholas J., Christianson, David W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454378/ https://www.ncbi.nlm.nih.gov/pubmed/28516954 http://dx.doi.org/10.1038/ncomms15368 |
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