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Advantages and Some Remaining Challenges in Hereditary Gastrointestinal Cancer Panel Testing
Colorectal cancer affects 1 in 20 men and women in their lifetime. About 30% of these cases have been shown to be familial while only about 5% are associated with a highly penetrant hereditary colon cancer syndrome. In many familial cases, however, no mutation in the commonly implicated CRC genes is...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454385/ https://www.ncbi.nlm.nih.gov/pubmed/28492537 http://dx.doi.org/10.1038/ctg.2017.19 |