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Effects of fumarates on inflammatory human astrocyte responses and oligodendrocyte differentiation

OBJECTIVE: Dimethyl fumarate (DMF) is a fumaric acid ester approved for the treatment of relapsing‐remitting multiple sclerosis (RRMS). In both the brain and periphery, DMF and its metabolite monomethyl fumarate (MMF) exert anti‐inflammatory and antioxidant effects. Our aim was to compare the effect...

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Detalles Bibliográficos
Autores principales: Galloway, Dylan A., Williams, John B., Moore, Craig S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454401/
https://www.ncbi.nlm.nih.gov/pubmed/28589165
http://dx.doi.org/10.1002/acn3.414