Microbial Natural Product Alternariol 5-O-Methyl Ether Inhibits HIV-1 Integration by Blocking Nuclear Import of the Pre-Integration Complex

While Highly Active Antiretroviral Therapy (HAART) has significantly decreased the mortality of human immunodeficiency virus (HIV)-infected patients, emerging drug resistance to approved HIV-1 integrase inhibitors highlights the need to develop new antivirals with novel mechanisms of action. In this...

Descripción completa

Detalles Bibliográficos
Autores principales: Ding, Jiwei, Zhao, Jianyuan, Yang, Zhijun, Ma, Ling, Mi, Zeyun, Wu, Yanbing, Guo, Jiamei, Zhou, Jinmin, Li, Xiaoyu, Guo, Ying, Peng, Zonggen, Wei, Tao, Yu, Haisheng, Zhang, Liguo, Ge, Mei, Cen, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454418/
https://www.ncbi.nlm.nih.gov/pubmed/28489061
http://dx.doi.org/10.3390/v9050105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454418/
https://www.ncbi.nlm.nih.gov/pubmed/28489061
http://dx.doi.org/10.3390/v9050105

Ejemplares similares