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Microbial Natural Product Alternariol 5-O-Methyl Ether Inhibits HIV-1 Integration by Blocking Nuclear Import of the Pre-Integration Complex
While Highly Active Antiretroviral Therapy (HAART) has significantly decreased the mortality of human immunodeficiency virus (HIV)-infected patients, emerging drug resistance to approved HIV-1 integrase inhibitors highlights the need to develop new antivirals with novel mechanisms of action. In this...
Autores principales: | Ding, Jiwei, Zhao, Jianyuan, Yang, Zhijun, Ma, Ling, Mi, Zeyun, Wu, Yanbing, Guo, Jiamei, Zhou, Jinmin, Li, Xiaoyu, Guo, Ying, Peng, Zonggen, Wei, Tao, Yu, Haisheng, Zhang, Liguo, Ge, Mei, Cen, Shan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454418/ https://www.ncbi.nlm.nih.gov/pubmed/28489061 http://dx.doi.org/10.3390/v9050105 |
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