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Human Beta Defensin 2 Selectively Inhibits HIV-1 in Highly Permissive CCR6(+)CD4(+) T Cells

Chemokine receptor type 6 (CCR6)(+)CD4(+) T cells are preferentially infected and depleted during HIV disease progression, but are preserved in non-progressors. CCR6 is expressed on a heterogeneous population of memory CD4(+) T cells that are critical to mucosal immunity. Preferential infection of t...

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Detalles Bibliográficos
Autores principales: Lafferty, Mark K., Sun, Lingling, Christensen-Quick, Aaron, Lu, Wuyuan, Garzino-Demo, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454423/
https://www.ncbi.nlm.nih.gov/pubmed/28509877
http://dx.doi.org/10.3390/v9050111