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A Role for the Host DNA Damage Response in Hepatitis B Virus cccDNA Formation—and Beyond?
Chronic hepatitis B virus (HBV) infection puts more than 250 million people at a greatly increased risk to develop end-stage liver disease. Like all hepadnaviruses, HBV replicates via protein-primed reverse transcription of a pregenomic (pg) RNA, yielding an unusually structured, viral polymerase-li...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454437/ https://www.ncbi.nlm.nih.gov/pubmed/28531167 http://dx.doi.org/10.3390/v9050125 |