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A Role for the Host DNA Damage Response in Hepatitis B Virus cccDNA Formation—and Beyond?

Chronic hepatitis B virus (HBV) infection puts more than 250 million people at a greatly increased risk to develop end-stage liver disease. Like all hepadnaviruses, HBV replicates via protein-primed reverse transcription of a pregenomic (pg) RNA, yielding an unusually structured, viral polymerase-li...

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Detalles Bibliográficos
Autores principales: Schreiner, Sabrina, Nassal, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454437/
https://www.ncbi.nlm.nih.gov/pubmed/28531167
http://dx.doi.org/10.3390/v9050125