A FKBP5 mutation is associated with Paget's disease of bone and enhances osteoclastogenesis

Paget's disease of bone (PDB) is a common metabolic bone disease that is characterized by aberrant focal bone remodeling, which is caused by excessive osteoclastic bone resorption followed by disorganized osteoblastic bone formation. Genetic factors are a critical determinant of PDB pathogenesi...

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Detalles Bibliográficos
Autores principales: Lu, Bingru, Jiao, Yulian, Wang, Yinchang, Dong, Jing, Wei, Muyun, Cui, Bin, Sun, Yafang, Wang, Laicheng, Zhang, Bingchang, Chen, Zijiang, Zhao, Yueran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454451/
https://www.ncbi.nlm.nih.gov/pubmed/28524179
http://dx.doi.org/10.1038/emm.2017.64

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454451/
https://www.ncbi.nlm.nih.gov/pubmed/28524179
http://dx.doi.org/10.1038/emm.2017.64

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