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Structure of the quaternary complex between SRP, SR, and translocon bound to the translating ribosome

During co-translational protein targeting, the signal recognition particle (SRP) binds to the translating ribosome displaying the signal sequence to deliver it to the SRP receptor (SR) on the membrane, where the signal peptide is transferred to the translocon. Using electron cryo-microscopy, we have...

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Detalles Bibliográficos
Autores principales: Jomaa, Ahmad, Fu, Yu-Hsien Hwang, Boehringer, Daniel, Leibundgut, Marc, Shan, Shu-ou, Ban, Nenad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454536/
https://www.ncbi.nlm.nih.gov/pubmed/28524878
http://dx.doi.org/10.1038/ncomms15470