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Surface chemistry governs cellular tropism of nanoparticles in the brain

Nanoparticles are of long-standing interest for the treatment of neurological diseases such as glioblastoma. Most past work focused on methods to introduce nanoparticles into the brain, suggesting that reaching the brain interstitium will be sufficient to ensure therapeutic efficacy. However, optimi...

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Detalles Bibliográficos
Autores principales: Song, Eric, Gaudin, Alice, King, Amanda R., Seo, Young-Eun, Suh, Hee-Won, Deng, Yang, Cui, Jiajia, Tietjen, Gregory T., Huttner, Anita, Saltzman, W. Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454541/
https://www.ncbi.nlm.nih.gov/pubmed/28524852
http://dx.doi.org/10.1038/ncomms15322