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Sensitive High-Resolution Melting Analysis for Screening of KRAS and BRAF Mutations in Iranian Human Metastatic Colorectal Cancers

BACKGROUND: Investigations of methods for detection of mutations have uncovered major weaknesses of direct sequencing and pyrosequencing, with their high costs and low sensitivity in screening for both known and unknown mutations. High resolution melting (HRM) analysis is an alternative tool for the...

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Detalles Bibliográficos
Autores principales: Niya, Mohammad Hadi Karbalaie, Basi, Ali, Koochak, Aghigh, Tameshkel, Fahimeh Safarnezhad, Rakhshani, Nasser, Zamani, Farhad, Imanzade, Farid, Rezvani, Hamid, sereshki, Mohammad Mahdi Adib, Sohrabi, Masoud Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454650/
https://www.ncbi.nlm.nih.gov/pubmed/28122448
http://dx.doi.org/10.22034/APJCP.2016.17.12.5147