Matrix Metalloproteinase Gene Activation Resulting from Disordred Epigenetic Mechanisms in Rheumatoid Arthritis

Matrix metalloproteinases (MMPs) are implicated in the degradation of extracellular matrix (ECM). Rheumatoid arthritis (RA) synovial fibroblasts (SFs) produce matrix-degrading enzymes, including MMPs, which facilitate cartilage destruction in the affected joints in RA. Epigenetic mechanisms contribu...

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Detalles Bibliográficos
Autores principales: Araki, Yasuto, Mimura, Toshihide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454818/
https://www.ncbi.nlm.nih.gov/pubmed/28441353
http://dx.doi.org/10.3390/ijms18050905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454818/
https://www.ncbi.nlm.nih.gov/pubmed/28441353
http://dx.doi.org/10.3390/ijms18050905

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