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Mutant p53 Protein and the Hippo Transducers YAP and TAZ: A Critical Oncogenic Node in Human Cancers

p53 protein is a well-known tumor suppressor factor that regulates cellular homeostasis. As it has several and key functions exerted, p53 is known as “the guardian of the genome” and either loss of function or gain of function mutations in the TP53 coding protein sequence are involved in cancer onse...

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Detalles Bibliográficos
Autores principales: Ferraiuolo, Maria, Verduci, Lorena, Blandino, Giovanni, Strano, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454874/
https://www.ncbi.nlm.nih.gov/pubmed/28467351
http://dx.doi.org/10.3390/ijms18050961