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Melatonin Promotes the In Vitro Development of Microinjected Pronuclear Mouse Embryos via Its Anti-Oxidative and Anti-Apoptotic Effects

CRISPR/Cas9 (Clustered regularly interspaced short palindromic repeats) combined with pronuclear microinjection has become the most effective method for producing transgenic animals. However, the relatively low embryo developmental rate limits its application. In the current study, it was observed t...

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Detalles Bibliográficos
Autores principales: Tian, Xiuzhi, Wang, Feng, Zhang, Lu, Ji, Pengyun, Wang, Jing, Lv, Dongying, Li, Guangdong, Chai, Menglong, Lian, Zhengxing, Liu, Guoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454901/
https://www.ncbi.nlm.nih.gov/pubmed/28475125
http://dx.doi.org/10.3390/ijms18050988