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Chloramidine/Bisindolylmaleimide-I-Mediated Inhibition of Exosome and Microvesicle Release and Enhanced Efficacy of Cancer Chemotherapy

Microvesicle (MV) release from tumour cells influences drug retention, contributing to cancer drug resistance. Strategically regulating MV release may increase drug retention within cancer cells and allow for lower doses of chemotherapeutic drugs. The contribution of exosomes to drug retention still...

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Detalles Bibliográficos
Autores principales: Kosgodage, Uchini S., Trindade, Rita P., Thompson, Paul R., Inal, Jameel M., Lange, Sigrun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454920/
https://www.ncbi.nlm.nih.gov/pubmed/28486412
http://dx.doi.org/10.3390/ijms18051007