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Unraveling Prion Protein Interactions with Aptamers and Other PrP-Binding Nucleic Acids

Transmissible spongiform encephalopathies (TSEs) are a group of neurodegenerative disorders that affect humans and other mammals. The etiologic agents common to these diseases are misfolded conformations of the prion protein (PrP). The molecular mechanisms that trigger the structural conversion of t...

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Detalles Bibliográficos
Autores principales: Macedo, Bruno, Cordeiro, Yraima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454936/
https://www.ncbi.nlm.nih.gov/pubmed/28513534
http://dx.doi.org/10.3390/ijms18051023