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Unraveling Prion Protein Interactions with Aptamers and Other PrP-Binding Nucleic Acids
Transmissible spongiform encephalopathies (TSEs) are a group of neurodegenerative disorders that affect humans and other mammals. The etiologic agents common to these diseases are misfolded conformations of the prion protein (PrP). The molecular mechanisms that trigger the structural conversion of t...
Autores principales: | Macedo, Bruno, Cordeiro, Yraima |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454936/ https://www.ncbi.nlm.nih.gov/pubmed/28513534 http://dx.doi.org/10.3390/ijms18051023 |
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