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The Effect of VPA on Increasing Radiosensitivity in Osteosarcoma Cells and Primary-Culture Cells from Chemical Carcinogen-Induced Breast Cancer in Rats

This study explored whether valproic acid (VPA, a histone deacetylase inhibitor) could radiosensitize osteosarcoma and primary-culture tumor cells, and determined the mechanism of VPA-induced radiosensitization. The working system included osteosarcoma cells (U2OS) and primary-culture cells from che...

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Detalles Bibliográficos
Autores principales: Liu, Guochao, Wang, Hui, Zhang, Fengmei, Tian, Youjia, Tian, Zhujun, Cai, Zuchao, Lim, David, Feng, Zhihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454939/
https://www.ncbi.nlm.nih.gov/pubmed/28489060
http://dx.doi.org/10.3390/ijms18051027