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A rapid and sensitive assay for quantification of siRNA efficiency and specificity

RNA Interference has rapidly emerged as an efficient procedure for knocking down gene expression in model systems. However, cross-reactivity, whereby multiple genes may be simultaneously targeted by a single short interfering RNA (siRNA), can potentially jeopardize correct interpretation of gene fun...

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Detalles Bibliográficos
Autores principales: Smart, Nicola, Scambler, Peter James, Riley, Paul Richard
Formato: Texto
Lenguaje:English
Publicado: Biological Procedures Online 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC545496/
https://www.ncbi.nlm.nih.gov/pubmed/15678169
http://dx.doi.org/10.1251/bpo99