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New Functions of APC/C Ubiquitin Ligase in the Nervous System and Its Role in Alzheimer’s Disease

The E3 ubiquitin ligase Anaphase Promoting Complex/Cyclosome (APC/C) regulates important processes in cells, such as the cell cycle, by targeting a set of substrates for degradation. In the last decade, APC/C has been related to several major functions in the nervous system, including axon guidance,...

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Detalles Bibliográficos
Autores principales: Fuchsberger, Tanja, Lloret, Ana, Viña, Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454969/
https://www.ncbi.nlm.nih.gov/pubmed/28505105
http://dx.doi.org/10.3390/ijms18051057